GHRP-2
Also known as Pralmorelin, Growth Hormone Releasing Peptide-2, KP-102
GHRP-2 (pralmorelin) is a hexapeptide ghrelin-receptor secretagogue, a second-generation GHRP. A research profile of where it sits among the growth-hormone-releasing peptides.
GHRP-2, also known as pralmorelin, is one of the growth-hormone-releasing peptides — a small family of synthetic hexapeptides that predate the selective secretagogues and share the same target, the ghrelin receptor. It is often described as a second-generation GHRP: more potent and more studied than the original GHRP-6, and one of the compounds against which newer, more selective agonists like ipamorelin are compared.
This page places GHRP-2 within that family. Chemistry and research context only — no dosing, no promised effects.
A synthetic hexapeptide (six residues) incorporating D-configured and non-natural amino acids, with an amidated C-terminus. Like the other GHRPs it is an agonist of the growth-hormone secretagogue receptor (GHS-R) — the ghrelin receptor — placing it on the secretagogue side of this cluster, not the GHRH-analog side.
Where GHRP-2 sits in the secretagogue family
The GHRPs — GHRP-2, GHRP-6 and hexarelin among them — are all ghrelin-receptor agonists, engaging GHS-R rather than the GHRH receptor. That firmly locates GHRP-2 on the secretagogue side of this product cluster, alongside ipamorelin and the non-peptide MK-677, and opposite the GHRH analogs sermorelin, tesamorelin and CJC-1295.
Within the GHRP subgroup, GHRP-2 is typically characterized as a robust, second-generation agonist. In research it has been noted, like the other early GHRPs, for a broader pituitary profile than the later selective secretagogues — a point of comparison rather than a value judgment.
A hexapeptide with non-natural residues
GHRP-2 is six amino acids long, but its sequence includes D-configured and non-standard residues and an amidated C-terminus, so it does not reduce to a clean list of the usual amino-acid codes. Certificates of analysis for it are read by mass and HPLC purity rather than by a recognizable residue string.
A single dominant HPLC peak and a mass matching the hexapeptide are the baseline checks; tie every lot to its own batch certificate.
These are research areas the compound is associated with in the literature — not medical claims or intended uses.
Handling & storage
Supplied lyophilized. Stored sealed and cold; reconstituted with bacteriostatic water only as a protocol requires, then refrigerated. Handle per accepted laboratory practice.
Verify a certificate by lot →Common questions
Both are hexapeptide ghrelin-receptor secretagogues. GHRP-2 (pralmorelin) is generally described as the more potent, second-generation peptide; GHRP-6 is the original of the series and is especially noted in research for hunger signaling.
No. GHRP-2 acts on the ghrelin (GHS) receptor, not the GHRH receptor. It belongs to the secretagogue side of the family with ipamorelin and MK-677.
Because it engages a different receptor from GHRH analogs, the two are studied together as complementary inputs to the growth-hormone axis.
This monograph is a research-use reference. It describes composition and the contexts in which the compound has been studied — it is not medical advice, a description of effects, or a recommendation for use. Sold strictly for laboratory and research use; not for human or animal consumption.